The perforated fold facilitates precise folding of a wide self-adhesive strip to form an airtight seal. Internal and external multiparameter process indicators for steam sterilization respond to three variables: time, temperature and saturated steam. The multiparameter process indicators printed directly on the pouch confirm sterilization parameters. Blue-tinted film makes it easy to view instruments and detect punctures or tears. Convenient thumb notch makes it easy to open the pouch without contaminating the contents.